Which is the bromide form of tiotropium?
Tiotropium Bromide is the bromide salt form of tiotropium, a quaternary ammonium derivative of atropine and a muscarinic receptor antagonist, with bronchodilating activity.
How is tiotropium bromide used to treat COPD?
Tiotropium Bromide Capsule, With Inhalation Device. Tiotropium is used to control and prevent symptoms (such as wheezing, shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD which includes bronchitis and emphysema).
How does tiotropium bromide work on muscarinic receptors?
Although it does not display selectivity for specific muscarinic receptors, on topical application, tiotropium bromide acts mainly on M3 muscarinic receptors located on smooth muscle cells and submucosal glands, preventing smooth muscle contraction and mucus secretion, thus producing a bronchodilatory effect.
Are there any side effects to taking tiotropium bromide?
Before using tiotropium, tell your doctor or pharmacist if you are allergic to it or to ipratropium; or to atropine or other belladonna -type drugs; or if you have any other allergies. This product may contain inactive ingredients (such as milk proteins), which can cause allergic reactions or other problems.
What are the impurities of tiotropium bromide API?
A muscarinic receptor antagonist, used in the treatment of chronic obstructive pulmonary disease (COPD). A long acting anticholinergic bronchodilator .Reference standards of Tiotropium Bromide API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Tiotropium Bromide Capsule, With Inhalation Device. Tiotropium is used to control and prevent symptoms (such as wheezing, shortness of breath) caused by ongoing lung disease (chronic obstructive pulmonary disease-COPD which includes bronchitis and emphysema).
How many MCG of Tiotropium is in a Spiriva capsule?
SPIRIVA HANDIHALER consists of SPIRIVA capsules and the HANDIHALER device. SPIRIVA capsules contain 18 mcg of tiotropium and are light green, with the Boehringer Ingelheim company logo on the
Before using tiotropium, tell your doctor or pharmacist if you are allergic to it or to ipratropium; or to atropine or other belladonna -type drugs; or if you have any other allergies. This product may contain inactive ingredients (such as milk proteins), which can cause allergic reactions or other problems.
