Do bisphosphonates affect teeth?
Do bisphosphonates affect teeth? As bisphosphonates have a mode of action that interferes with the bone resorption by osteoclasts, they can have side effects in dental treatment, including inhibited tooth movement, impaired bone healing, and induced osteonecrosis in the maxilla and the mandible. What are contraindications to bisphosphonates? Contraindications to bisphosphonates include: History of hypersensitivity to the bisphosphonate. Hypocalcemia. Chronic kidney disease with a glomerular filtration rate of less than 30 to 35 mL/min. What are the two main adverse effects of bisphosphonates? General side effects of bisphosphonates and denosumabFever and flu-like symptoms. Low levels of calcium in your blood...