What is atropine sulphate used for?
Atropine Sulfate Injection is used: as a preoperative medication for the reduction of salivary and bronchial secretions. during cardiopulmonary resuscitation to treat sinus bradycardia or asystole.
What type of drug is atropine sulfate?
Atropine Solution belongs to a class of drugs called Anticholinergic, Antispasmodic Agents.
Is atropine a sulfa drug?
Sulfa-based eye drops like Genoptic (gentamicin sulfate), Polytrim (polymyxin B/trimethoprim), atropine sulfate, and Maxitrol (neomycin/dexamethasone/polymyxin B) are safe to use in those with reported sulfa allergies.
What is the action of atropine sulfate?
Mechanism of action. The most important therapeutic action of atropine is the inhibition of smooth muscle and glands innervated by postganglionic cholinergic nerves. It also has central nervous system activity, which may be stimulating or depressing depending upon the dose.
How does atropine treat nerve agents?
Atropine sulphate is an essential drug in the treatment of nerve agent poisoning. It acts by blocking the effects of acetylcholine at muscarinic receptors and so produces relief from many of the symptoms previously listed.
What is the indication of atropine?
Atropine or atropine sulfate carries FDA indications for anti-sialagogue/anti-vagal effect, organophosphate/muscarinic poisoning, and bradycardia. Atropine acts as a competitive, reversible antagonist of muscarinic receptors: an anticholinergic drug.
What are the side effects of atropine sulfate?
When do you take atropine sulfate eye drops?
Atropine SULFATE Drops. This medication is used before eye examinations (e.g., refraction) and to treat certain eye conditions (e.g., uveitis). It belongs to a class of drugs known as anticholinergics.
Which is the correct chemical name for atropine sulfate?
Atropine, a naturally occurring belladonna alkaloid, is a racemic mixture of equal parts of d- and 1-hyocyamine, whose activity is due almost entirely to the levo isomer of the drug. Sodium Chloride, USP is chemically designated NaCl, a white crystalline powder freely soluble in water.
How many mg of atropine is in a mL of ophthalmic solution?
Each mL of Atropine Sulfate Ophthalmic Solution USP, 1% contains: Active: atropine sulfate 10 mg equivalent to 8.3 mg of atropine.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: redness of the face, neck, arms, and occasionally, upper chest Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
How is atropine sulfate used to treat lazy eyes?
It is also used to treat an eye condition called amblyopia (lazy eyes) and other eye conditions (eg, cycloplegia). Atropine sulfate works by blocking the chemical acetylcholine, which relaxes the ciliary muscle of the eye and causes the pupil to dilate.
What is the bioavailability of atropine sulfate ophthalmic solution?
The bioavailability of atropine sulfate ophthalmic solution, USP 1% was assessed in six healthy subjects, 24 to 29 years of age. Subjects received either 0.3 mg atropine sulfate administered as bolus intravenous injection or 0.3 mg administered as 30 μl instilled unilaterally in the cul-de-sac of the eye.
When to use atropine ophthalmic solution in children?
Pediatric Use. Due to the potential for systemic absorption of atropine sulfate ophthalmic solution, the use of atropine sulfate ophthalmic solution, USP 1% in children under the age of 3 months is not recommended and the use in children under 3 years of age should be limited to no more than one drop per eye per day.
