What is a Tildren for horses?
Tildren® (tiludronate) has been used for a number of years by veterinarians in Europe to treat joint conditions such as navicular disease and bone spavin. In adult horses, normal skeletal bone tissue is undergoing a process of continuous turnover. …
How do you use Tildren?
A single dose of TILDREN should be administered as an intravenous infusion at a dose of 1 mg/kg (0.45 mg/lb). The infusion should be administered slowly and evenly over 90 minutes to minimize the risk of adverse reactions. Maximum effect may not occur until 2 months post-treatment.
Does OSPHOS relieve pain?
Now there’s a drug that can actually inhibit bone degeneration—and thereby reduce pain. Osphos (pronounced “Oz-foz”) is made by Dechra Veterinary Products—the same folks who came out with IRAP serum. It was approved by the FDA in May and became commercially available in October.
Is OSPHOS safe for horses?
Because bisphosphonates inhibit osteoclast activity and decrease bone turnover, these drugs may negatively affect bone growth and bone health. The safe use of either TILDREN or OSPHOS has not been evaluated in breeding horses or pregnant or lactating mares.
How long does it take for OSPHOS to start working?
It may take two months to see the maximum effect. You administer OSPHOS by intramuscular injection. The total volume should be divided equally into three injection sites. Similar to TILDREN, it may take two months to see the most clinical improvement.
What is Tildren used for?
Two equine drugs—TILDREN distributed by Bimeda Animal Health Limited and OSPHOS distributed by Dechra, Ltd. — are FDA-approved to control the clinical signs of navicular syndrome, a common cause of forelimb lameness in horses.
What are the side effects of Osphos in horses?
What adverse reactions are caused by OSPHOS?
- Renal failure;
- Polyuria;
- Polydipsia;
- Abdominal pain;
- Anorexia;
- Lethargy;
- Hypercalcemia;
- Abnormal behavior, such as head shaking, flehmen response, and lip licking;
What does Osphos do for horses?
OsPhos is an FDA approved, injectable bisphosphonate solution labeled for the control of clinical signs associated with navicular syndrome (caudal heal pain) in horses four years and older. OsPhos inhibits bone resorption (disappearance) by inhibiting cells called osteoclasts.
