What lab tests are available to establish the diagnosis of Lyme disease?

What lab tests are available to establish the diagnosis of Lyme disease?

Enzyme immunoassay (EIA) An enzyme immunoassay is used as a screening test to detect IgM and/or IgG antibodies in serum that are directed against the bacterium that causes LYME DISEASE. Commercial kits, such as an enzyme-linked immunosorbent assay, rely on the use of whole-cell preparations of B.

Would Lyme disease show up on CBC?

In patients with clinical findings typical of Lyme disease, a complete blood cell count (CBC), erythrocyte sedimentation rate (ESR), and liver function tests generally are unnecessary. However, leukopenia or thrombocytopenia suggests co-infection with Ehrlichia or Babesia species.

How are laboratory tests used to diagnose Lyme disease?

Laboratory tests that can help confirm the clinical diagnosis of Lyme disease include various serologic techniques and polymerase chain reaction (PCR)-based assays, as summarized in Table 2. Table 2. Tests Available for Diagnosis and Management of Lyme Disease [return to contents]

Is there a blood test for Lyme disease in Ontario?

Unfortunately, the blood testing for Lyme disease in Ontario is not always adequate to rule out this disease definitively, and there are often false negatives. Therefore, when Dr. Kim suspects this disease in a patient she sends bloodwork to IGeneX, a lab specializing in the testing and diagnosis of Lyme Disease.

How can you tell if you have Lyme disease?

Lyme disease is an infection caused by bacteria carried by ticks. Lyme disease tests look for signs of infection in your blood or cerebrospinal fluid.

When to disregard a positive Lyme disease test?

Some tests give results for two types of antibody, IgM and IgG. Positive IgM results should be disregarded if the patient has been ill for more than 30 days. New tests may be developed as alternatives to one or both steps of the two-step process. Before CDC will recommend new tests, they must be cleared by the Food and Drug Administration (FDA).

What is the most accurate test for Lyme disease?

The most accurate way to detect Lyme disease is with a two-stage blood test. The first is a screening test called an enzyme-linked immunosorbent assay (often referred to as ELISA) that looks for certain antibodies (immune proteins) that are the immune system’s response to the infection.

What blood test is taken for Lyme disease?

The most common blood tests for Lyme The two most common diagnostic tests for Lyme disease are the enzyme-linked immunosorbent assay (ELISA) and the Western blot . These tests allow physicians to visualize the reaction between antibodies in an infected person’s blood to specific antigens, or parts of the bacteria that causes Lyme disease.

What are the diagnostic tests for Lyme disease?

Two-tier Testing. The most common diagnostic tests for Lyme disease are indirect ones. They measure the patient’s antibody response to the infection, not the infection itself. The two most-used antibody tests are the enzyme-linked immunosorbent assay (ELISA) and the Western blot.

Is there a definitive test for Lyme disease?

The IgM and IgG tests are performed first. If you test positive for these antibodies, it’s likely that you have or had Lyme disease. A positive result on the ELISA test means Lyme disease is likely, but must be confirmed with a Western blot. The Western blot test is the definitive diagnosis for Lyme disease.