When to use sulfamethoxazole and trimethoprim together?
What is sulfamethoxazole and trimethoprim? Sulfamethoxazole and trimethoprim is a combination antibiotic used to treat ear infections, urinary tract infections, bronchitis, traveler’s diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia. Sulfamethoxazole and trimethoprim may also be used for purposes not listed in this medication guide.
What kind of infections can trimethoprim be used for?
Sulfamethoxazole and trimethoprim are both antibiotics that treat different types of infection caused by bacteria. Sulfamethoxazole and trimethoprim is used a combination antibiotic used to treat ear infections, urinary tract infections, bronchitis, traveler’s diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.
When do sulfatrim and trimethoprim show up in the blood?
However, patients with severely impaired renal function exhibit an increase in the half-lives of both components, requiring dosage regimen adjustment (see DOSAGE AND ADMINISTRATION section). Detectable amounts of sulfamethoxazole and trimethoprim are present in the blood 24 hours after drug administration.
What is the effect of trimethoprim on folic acid synthesis?
Trimethoprim inhibits dihydrofolate reductase, the enzyme that catalyzes the last step of bacterial folic acid synthesis (see Fig. 4-7 ). Trimethoprim, although available as a single agent, is seldom used this way. Instead, trimethoprim is nearly always used in combination with sulfamethoxazole for synergistic effects.
What is sulfamethoxazole and trimethoprim? Sulfamethoxazole and trimethoprim is a combination antibiotic used to treat ear infections, urinary tract infections, bronchitis, traveler’s diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia. Sulfamethoxazole and trimethoprim may also be used for purposes not listed in this medication guide.
Sulfamethoxazole and trimethoprim are both antibiotics that treat different types of infection caused by bacteria. Sulfamethoxazole and trimethoprim is used a combination antibiotic used to treat ear infections, urinary tract infections, bronchitis, traveler’s diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.
However, patients with severely impaired renal function exhibit an increase in the half-lives of both components, requiring dosage regimen adjustment (see DOSAGE AND ADMINISTRATION section). Detectable amounts of sulfamethoxazole and trimethoprim are present in the blood 24 hours after drug administration.
Trimethoprim inhibits dihydrofolate reductase, the enzyme that catalyzes the last step of bacterial folic acid synthesis (see Fig. 4-7 ). Trimethoprim, although available as a single agent, is seldom used this way. Instead, trimethoprim is nearly always used in combination with sulfamethoxazole for synergistic effects.
