What is Trimethobenzamide Hydrochloride used for?
Trimethobenzamide is used to treat nausea and vomiting that may occur after surgery. It is also used to control nausea caused by gastroenteritis (‘stomach flu’; a virus that may cause nausea, vomiting, and diarrhea).
How long does it take for trimethobenzamide to work?
The time to reach maximum plasma concentration (Tmax) was about 30 minutes after intramuscular injection compared to about 45 minutes after oral capsule administration.
Is trimethobenzamide still available?
All generic trimethobenzamide oral capsules have been discontinued. Pfizer discontinued oral Tigan. They expect supplies to be depleted by May 2021. Trimethobenzamide injection is not affected by this shortage.
Does Tigan make you drowsy?
SIDE EFFECTS: Diarrhea, headache, dizziness, drowsiness, blurred vision, or muscle cramps may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Is Trimethobenzamide a controlled substance?
TIGAN 250 mg (Tigan 250 MG) Tigan is used in the treatment of nausea/vomiting and belongs to the drug class anticholinergic antiemetics. FDA has not classified the drug for risk during pregnancy. Tigan 250 MG is not a controlled substance under the Controlled Substances Act (CSA).
Why is trimethobenzamide being discontinued?
Reason for shortage: All generic trimethobenzamide oral capsules have been discontinued. Pfizer did not provide a reason for the shortage of Tigan capsules.
What is the best anti emetic?
Antiemetics for cancer and chemotherapy
- aprepitant (Emend)
- dexamethasone (DexPak)
- dolasetron (Anzemet)
- granisetron (Kytril)
- ondansetron (Zofran)
- palonosetron (Aloxi)
- prochlorperazine (Compazine)
- rolapitant (Varubi)
When do you use Tigan?
BRAND NAME(S): Tigan. USES: This medication is used to treat nausea and vomiting that can occur following surgery or with certain stomach/intestinal problems (e.g., gastroenteritis). Treating vomiting quickly can prevent a serious loss of body water (dehydration).
What class of medication is Tigan?
Trimethobenzamide belongs to a class of drugs known as antiemetics. It works by decreasing the signals in the brain that lead to vomiting.
How long does Tigan injection last?
The mean elimination half-life of trimethobenzamide is 7 to 9 hours. Between 30 – 50% of a single dose in humans is excreted unchanged in the urine within 48 – 72 hours.
