Why is interferon a treatment for warts?
Background. Interferon has been widely used in the treatment of genital warts for its immunomodulatory, antiproliferative and antiviral properties. Currently, no evidence that interferon improves the complete response rate or reduces the recurrence rate of genital warts has been generally provided.
Can interferon cure HPV?
There are no consistently effective treatment options for disseminated human papillomavirus (HPV) infection [1]. Interferons have been shown to have some efficacy in treatment of genital warts, but local treatments have appeared to have produced better results than systemic treatments in previous studies [2].
How can interferons be used to treat diseases?
Interferons are man-made versions of proteins your body makes. These drugs work with your immune system to help it find and attack viruses and cancer. They can stop virus and cancer cells from growing and spreading, and prevent other cells from getting infected.
Which interferon is used for the treatment of venereal warts?
Interferon alfa is used for intralesional treatment of external anogenital warts and condyloma acuminatum. It is injected into the base of each wart, preferably via a 30-gauge needle, in a dosage of 3 million IU 3 times per week for 3 weeks.
Can HPV disseminate?
HPV type 11 is a mucosal type of virus and infects the genital tract or larynx. Disseminated HPV-11 infection involving multiple body sites in cases of pemphigus vulgaris (PV) has not been reported.
Can interferons be used for Covid-19?
Recommendation. The COVID-19 Treatment Guidelines Panel recommends against the use of interferons for the treatment of patients with severe or critical COVID-19, except in a clinical trial (AIII).
Is HPV systemic?
It used to be oral cancer was attributed primarily to tobacco users, but an oral systemic link has been established indicating at least 3% of the U.S. population had one or more oncogenic HPV types present in their saliva.
Is interferon an immunotherapy?
Interferon is a type of immunotherapy patients receive as adjuvant therapy to reduce the risk of melanoma relapse.
What stimulates interferon production?
Interferon is secreted by cells in response to stimulation by a virus or other foreign substance, but it does not directly inhibit the virus’s multiplication. Rather, it stimulates the infected cells and those nearby to produce proteins that prevent the virus from replicating within them.
