What is a refl Titer?

RPR (Diagnosis) with Reflex to Titer and Confirmatory Testing (REFL) – This is a non-treponemal screening test for syphilis. False positive results may occur due to systemic lupus erythematosus, leprosy, brucellosis, atypical pneumonia, typhus, yaws, pinta, or pregnancy.

Is RPR confirmatory for syphilis?

A rapid plasma reagin (RPR) test is a blood test used to screen you for syphilis. It works by detecting the nonspecific antibodies that your body produces while fighting the infection. Syphilis is a sexually transmitted infection (STI) caused by the spirochete bacterium Treponema pallidum.

What does RPR DX test for?

RPR (rapid plasma reagin) is a screening test for syphilis . It measures substances (proteins) called antibodies that are present in the blood of people who may have the disease.

What is RPR reflex to T pallidum?

Reagin antibodies are non-treponemal antibodies produced by the body’s defense mechanism in response to an infection with Treponema pallidum. If the RPR is reactive, a quantitative titer and a TP-PA will be done. The TP-PA test is a confirmatory treponemal pallidum particle agglutination test.

What is a high RPR titer?

A positive RPR test should be followed by another type of test to diagnose syphilis. If you have been treated for syphilis in the past, an RPR test that shows a titer increase of fourfold means you likely have a new syphilis infection if you were not fully treated in the past.

What is considered a positive RPR titer?

A positive titer with a VDRL or RPR indicates active syphilis and follow-up serologic testing is performed to monitor treatment response. With this new testing algorithm that uses the treponemal test first, some patients may test positive for a treponemal test but test negative with a nontreponemal test.

What is considered a low RPR titer?

However, the RPR may remain reactive at a low titer (generally <1:8), a condition referred to as the serofast state.

What is the ICD 10 code for syphilis?

A53. 9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

What color tube is used for VDRL?

The VDRL is a non-treponemal-specific test; therefore, a treponemal-specific confirmatory test should be performed unless prior syphilis infection has been documented for this patient. SPECIMEN REQUIREMENTS: Draw blood in a plain red-top tube(s), serum gel tube(s) is acceptable.