What is the adverse effect of theophylline?

Nausea/vomiting, stomach/abdominal pain, headache, trouble sleeping, diarrhea, irritability, restlessness, nervousness, shaking, or increased urination may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

What are the concerns for patients on theophylline therapy?

Many of the typical symptoms of theophylline toxicity are non-specific, which further perpetuates the challenges of recognition in a long-term user. These include nausea, vomiting, fatigue, tachycardia and central nervous system (CNS) effects such as dizziness and seizures [3].

How quickly does theophylline work?

This medication should take effect within 1 to 2 days, and you should see improvements in your pet’s clinical signs.

How long can you take theophylline?

Adult dosage (ages 18–59 years) After 3 days, your dose may be increased to 400–600 mg per day if you don’t have any side effects. After 3 more days, if your dose is tolerated and more medication is needed, your dose may be adjusted based on the level of theophylline in your blood.

Which tea has theophylline?

Theophylline is found in black tea and to a lesser extent in green coffee, cocoa cotyledon and dried mate. Theophylline is synthesized on an industrial scale and is used principally in pharmaceutical preparations. Per-caput daily intake of theophylline from black tea in the USA has been estimated to be 0.14 mg.

Can you drink coffee with theophylline?

theophylline caffeine Avoid drinks or foods that contain caffeine, such as coffee, tea, cola, and chocolate. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs.

Do doctors still prescribe theophylline?

While theophylline has been used in the treatment of asthma since 1922, it has since fallen in and out of favor with doctors and, today, is not as commonly used as it once was.

How much theophylline is in deriphyllin 150 mg?

Each film coated prolonged release Deriphyllin (R) 150 mg tablet contains Etophylline 115 mg, Theophylline Anhydrous equivalent to Theophylline Hydrate 35 mg and Excipients q.s. Deriphyllin (R) 150 mg tablet is used to prescribe for the treatment of:

What are the side effects of theophylline extended release tablets?

Theophylline extended-release tablets are indicated for the treatment of the symptoms and reversible airflow obstruction associated with chronic asthma and other chronic lung diseases, e.g., emphysema and chronic bronchitis.

How much theophylline can you take in one day?

Theophylline: Initially, 12–14 mg/kg (maximum 300 mg) daily in divided doses; after 3 days, if tolerated, increase dosage to maximum 16 mg/kg (maximum 400 mg) daily in divided doses Monitor serum theophylline concentrations at 24-hour intervals to adjust final dosage. 226 f For final dosage titration, see Table 2.

What should the serum concentration of theophylline be?

In general, maintaining peak serum Theophylline concentrations between 10 and 15 mcg/mL will achieve most of the drug’s potential therapeutic benefit while minimizing the risk of serious adverse events.

Are there any side effects to taking theophylline?

However, adenosine antagonism is likely to account for the serious side effects of theophylline, such as seizures and cardiac arrhythmias, via blockade of A 1 receptors. IL-10 has a broad spectrum of antiinflammatory effects, and its secretion is reduced in asthma and COPD.

Why is theophylline used as a third-line treatment?

Despite its widespread global use, in industrialized countries theophylline has become a third-line treatment as an add-on therapy in patients with poorly controlled disease, because inhaled β 2 -agonists are far more effective as bronchodilators, and inhaled corticosteroids have a greater antiinflammatory effect.

How many times a day should you take theophylline?

Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Your dose and the number of times you take theophylline daily will depend on the reason you are taking this medication. Follow your doctor’s instructions about whether to take your medication with food or on an empty stomach.

When to seek medical attention for theophylline overdose?

Never use theophylline in larger amounts, or for longer than prescribed. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working as well. Overdose can occur if you take too much theophylline at one time, or if your daily doses are too high.